null

SMILES COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC

InChI Key InChIKey=IEDVJHCEMCRBQM-UHFFFAOYSA-N

PDB links: 28 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 18069   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Concentration of the compound inhibiting T. gondii dihydrofolate reductase .More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736PXGPubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Concentration of the compound inhibiting P. carinii dihydrofolate reductase .More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+5nMAssay Description:Concentration inhibiting rat liver dihydrofolate reductase .More data for this Ligand-Target Pair