null
SMILES Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1
InChI Key InChIKey=HTUBKQUPEREOGA-UHFFFAOYSA-N
PDB links: 4 PDB IDs match this monomer. 2 PDB IDs contain inhibitors having a similarity of 90% to this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 4567
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£ degli Studi di Parma
Curated by ChEMBL
Universit£ degli Studi di Parma
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells incubated for 1 hr followed by compound washout measured at 1 hr by Western blot...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£ degli Studi di Parma
Curated by ChEMBL
Universit£ degli Studi di Parma
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells incubated for 1 hr followed by compound washout measured after 8 hrs by Western ...More data for this Ligand-Target Pair