null

SMILES O=C(Cc1ccccc1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccc3)s2)s1

InChI Key InChIKey=MDJIPXYRSZHCFS-UHFFFAOYSA-N

PDB links: 7 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50400050   

TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400050(CHEMBL2177757 | US10793535, Cmpd ID 1 | US11191732...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin) assessed as NADH formation using 10 mM glutamine as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400050(CHEMBL2177757 | US10793535, Cmpd ID 1 | US11191732...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human GAC assessed as NADH formation using 10 mM glutamine as substrateMore data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400050(CHEMBL2177757 | US10793535, Cmpd ID 1 | US11191732...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin) assessed as NADH formation using 1.8 to 13 mM glutamine as substrate preincubated for 60 mins by resorufin dye bas...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400050(CHEMBL2177757 | US10793535, Cmpd ID 1 | US11191732...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of human KGA (1 to 669 residues) preincubated for 20 mins using 7 mM glutamine as substrateMore data for this Ligand-Target Pair