null
SMILES COc1ccc(CCN2CCC(CC2)Nc2nc(NCc3ccc(F)cc3)nc3cc(OC)c(OC)cc23)cc1
InChI Key InChIKey=XFJVKNMVYFKSRX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50506782
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Universit£ de Lille
Curated by ChEMBL
Universit£ de Lille
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 3A(Homo sapiens (Human))
Universit£ de Lille
Curated by ChEMBL
Universit£ de Lille
Curated by ChEMBL
Affinity DataEC50: 5.20E+3nMAssay Description:Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) using 5'-biotinylated/3'-FAM-oligonucleotide as substrate me...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Universit£ de Lille
Curated by ChEMBL
Universit£ de Lille
Curated by ChEMBL
Affinity DataEC50: 3.18E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-fused G9a (786 to 1210 residues) expressed in Escherichia coli using biotinylated H3 (1 to 21 residues...More data for this Ligand-Target Pair