null
SMILES O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
InChI Key InChIKey=NYNZQNWKBKUAII-KBXCAEBGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 136597
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
University of Arkansas for Medical Sciences
Curated by ChEMBL
University of Arkansas for Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of TRKA (unknown origin) by FISH assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
University of Arkansas for Medical Sciences
Curated by ChEMBL
University of Arkansas for Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of TRKA G667C mutant (unknown origin) using poly-EAY peptide as substrate in presence of gamma-33ATP by LanthaScreen assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
University of Arkansas for Medical Sciences
Curated by ChEMBL
University of Arkansas for Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of TRKA G595R mutant (unknown origin) using poly-EAY peptide as substrate in presence of gamma-33ATP by LanthaScreen assayMore data for this Ligand-Target Pair