null

SMILES Cc1nc(C(=O)NCC(O)=O)c(O)c2ccc(Oc3ccccc3)cc12

InChI Key InChIKey=YOZBGTLTNGAVFU-UHFFFAOYSA-N

PDB links: 5 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50431015   

TargetProlyl 4-hydroxylase(Paramecium bursaria Chlorella virus 1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50431015(CHEMBL2338329 | US10889546, FG-4592 | US9115085, C...)copy SMILEScopy InChI
Affinity DataKi:  1.07E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9G4RPubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50431015(CHEMBL2338329 | US10889546, FG-4592 | US9115085, C...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human PHD2 using 2OG as substrate and Fe2 as co-factor assessed as hydroxylation incubated for 15 mins in presence of L-asc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9G4RPubMed
TargetProlyl 4-hydroxylase(Paramecium bursaria Chlorella virus 1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50431015(CHEMBL2338329 | US10889546, FG-4592 | US9115085, C...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9G4RPubMed
TargetHypoxia-inducible factor 1-alpha inhibitor(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50431015(CHEMBL2338329 | US10889546, FG-4592 | US9115085, C...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human FIH using 2OG as substrate and Fe2 as co-factor assessed as hydroxylation incubated for 15 mins in presence of L-asco...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9G4RPubMed
TargetProlyl 3-hydroxylase OGFOD1(Homo sapiens)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50431015(CHEMBL2338329 | US10889546, FG-4592 | US9115085, C...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human OGFOD1 using 2OG as substrate and Fe2 as co-factor assessed as hydroxylation incubated for 15 mins in presence of L-a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9G4RPubMed