null
SMILES NCCCC(O)=O
InChI Key InChIKey=BTCSSZJGUNDROE-UHFFFAOYSA-N
PDB links: 80 PDB IDs match this monomer. 551 PDB IDs contain this monomer as substructures. 551 PDB IDs contain inhibitors having a similarity of 90% to this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 24183
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 3.70E+3nMAssay Description:Agonist activity at recombinant human GABA-A alpha1beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 3.80E+3nMAssay Description:Agonist activity at recombinant human GABA-A alpha1beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 2(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human GAT2 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human GAT3 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-2/gamma-2(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 3.72E+3nMAssay Description:Agonist activity at recombinant human GABA-A alpha4beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 339nMAssay Description:Agonist activity at recombinant human GABA-A rho-1 receptor transiently expressed in human tsA201 cells incubated for 30 mins and measured up to 90 s...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GAT1 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BGT1 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 340nMAssay Description:Agonist activity at recombinant human GABA-A rho-1 receptor transiently expressed in human tsA201 cells incubated for 30 mins and measured up to 90 s...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 230nMAssay Description:Agonist activity at recombinant human GABA-A alpha5beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-2/gamma-2(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 3.70E+3nMAssay Description:Agonist activity at recombinant human GABA-A alpha4beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 234nMAssay Description:Agonist activity at recombinant human GABA-A alpha5beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...More data for this Ligand-Target Pair