null
SMILES Cc1nc2c(s1)C(=O)C\C(=N/c1ccc(C)cc1)C2=O
InChI Key InChIKey=CANBMWXJDLUDFF-GZTJUZNOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50075100
TargetN-lysine methyltransferase KMT5A(Homo sapiens (Human))
The Center for Combinatorial Chemistry and Drug Discovery of Jilin University
Curated by ChEMBL
The Center for Combinatorial Chemistry and Drug Discovery of Jilin University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal His6-tagged human SETD8 (191 to 352 residues) expressed in Escherichia coli Rosseta-2(DE3) cells using histone peptide subst...More data for this Ligand-Target Pair
TargetN-lysine methyltransferase KMT5A(Homo sapiens (Human))
The Center for Combinatorial Chemistry and Drug Discovery of Jilin University
Curated by ChEMBL
The Center for Combinatorial Chemistry and Drug Discovery of Jilin University
Curated by ChEMBL
Affinity DataEC50: <1.00E+3nMAssay Description:Inhibition of SETD8 in HEK293T cells assessed as reduction in H4K20me level after 2 to 3 days by Western blot analysisMore data for this Ligand-Target Pair