null
SMILES Cn1cnc2c(NCc3ccccc3)nc(NCCO)nc12
InChI Key InChIKey=GTVPOLSIJWJJNY-UHFFFAOYSA-N
PDB links: 2 PDB IDs match this monomer. 5 PDB IDs contain this monomer as substructures. 5 PDB IDs contain inhibitors having a similarity of 90% to this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 5718
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH
Curated by ChEMBL
Aventis Pharma Deutschland GmbH
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Cyclin A-cyclin-dependent kinase 2More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH
Curated by ChEMBL
Aventis Pharma Deutschland GmbH
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Cyclin B-cyclin-dependent kinase 1More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH
Curated by ChEMBL
Aventis Pharma Deutschland GmbH
Curated by ChEMBL
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of cAMP-dependent protein kinaseMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH
Curated by ChEMBL
Aventis Pharma Deutschland GmbH
Curated by ChEMBL
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Cyclin D1-cyclin-dependent kinase 4More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH
Curated by ChEMBL
Aventis Pharma Deutschland GmbH
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Cyclin E-cyclin-dependent kinase 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH
Curated by ChEMBL
Aventis Pharma Deutschland GmbH
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Mitogen-activated protein kinase 3 (MAPK-ERK1)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH
Curated by ChEMBL
Aventis Pharma Deutschland GmbH
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase 1 (MAPK-ERK2)More data for this Ligand-Target Pair