null

SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=AEJOEPSMZCEYJN-HXUWFJFHSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50007344   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor Corporation

Curated by ChEMBL
LigandPNGBDBM50007344((S)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2...)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Inhibitory constant against human Opioid receptor kappa using [3H]-diprenorphine as radio ligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7VH4PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor Corporation

Curated by ChEMBL
LigandPNGBDBM50007344((S)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2...)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:Inhibitory constant against human Opioid receptor delta 1 using [3H]diprenorphine as radio ligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7VH4PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor Corporation

Curated by ChEMBL
LigandPNGBDBM50007344((S)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2...)copy SMILEScopy InChI
Affinity DataKi:  53nMAssay Description:Inhibitory constant against human Opioid receptor mu 1 using [3H]diprenorphine as radio ligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7VH4PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Adolor Corporation

Curated by ChEMBL
LigandPNGBDBM50007344((S)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of cytochrome P450 2D6 was determined using MAMC (7-methoxy-4-aminomethyl-coumarin) as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7VH4PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor Corporation

Curated by ChEMBL
LigandPNGBDBM50007344((S)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2...)copy SMILEScopy InChI
Affinity DataEC50:  0.300nMAssay Description:Inhibitory constant against human Opioid receptor kappa using [3H]diprenorphine as radio ligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7VH4PubMed