null

SMILES NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1

InChI Key InChIKey=XNSAINXGIQZQOO-SRVKXCTJSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50072394   

TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyr...)copy SMILEScopy InChI
Affinity DataKi:  10nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FQGPubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyr...)copy SMILEScopy InChI
Affinity DataKi:  20nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FQGPubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyr...)copy SMILEScopy InChI
Affinity DataEC50:  3nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FQGPubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyr...)copy SMILEScopy InChI
Affinity DataEC50:  3nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FQGPubMed