null

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(NC(=O)c3cc4ccccc4cn3)cc2)no1

InChI Key InChIKey=YRUDYNCGPZHXRB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50310628   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Ambit Biosciences Inc.

Curated by ChEMBL
LigandPNGBDBM50310628(AB-460 | CHEMBL1081509 | N-(4-(3-(5-tert-butylisox...)copy SMILEScopy InChI
Affinity DataKd: >200nMAssay Description:Binding affinity to VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1RVBPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences Inc.

Curated by ChEMBL
LigandPNGBDBM50310628(AB-460 | CHEMBL1081509 | N-(4-(3-(5-tert-butylisox...)copy SMILEScopy InChI
Affinity DataKd:  1.10nMAssay Description:Binding affinity to FLT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1RVBPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences Inc.

Curated by ChEMBL
LigandPNGBDBM50310628(AB-460 | CHEMBL1081509 | N-(4-(3-(5-tert-butylisox...)copy SMILEScopy InChI
Affinity DataKd:  1.80nMAssay Description:Binding affinity to KITMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1RVBPubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Ambit Biosciences Inc.

Curated by ChEMBL
LigandPNGBDBM50310628(AB-460 | CHEMBL1081509 | N-(4-(3-(5-tert-butylisox...)copy SMILEScopy InChI
Affinity DataKd:  8.5nMAssay Description:Binding affinity to CSF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1RVBPubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Ambit Biosciences Inc.

Curated by ChEMBL
LigandPNGBDBM50310628(AB-460 | CHEMBL1081509 | N-(4-(3-(5-tert-butylisox...)copy SMILEScopy InChI
Affinity DataKd:  9.90nMAssay Description:Binding affinity to PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1RVBPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Ambit Biosciences Inc.

Curated by ChEMBL
LigandPNGBDBM50310628(AB-460 | CHEMBL1081509 | N-(4-(3-(5-tert-butylisox...)copy SMILEScopy InChI
Affinity DataKd:  7nMAssay Description:Binding affinity to PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1RVBPubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ambit Biosciences Inc.

Curated by ChEMBL
LigandPNGBDBM50310628(AB-460 | CHEMBL1081509 | N-(4-(3-(5-tert-butylisox...)copy SMILEScopy InChI
Affinity DataKd:  7.30nMAssay Description:Binding affinity to RETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1RVBPubMed