null

SMILES NC1=NC2(CCN(CC2)C(=O)c2ccc(nc2)C#N)Nc2c(F)ccc(F)c12

InChI Key InChIKey=GIZYIOOBBUHOBS-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124535   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Charnwood

Curated by ChEMBL
LigandPNGBDBM50124535(1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5N4SPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca Charnwood

Curated by ChEMBL
LigandPNGBDBM50124535(1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of iNOS in intact human DLD1 cells assessed as nitric oxide productionMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca Charnwood

Curated by ChEMBL
LigandPNGBDBM50124535(1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair