null

SMILES COc1cc2CCN(CCc3ccc(NC(=O)c4cccc5c4[nH]c4c(OC)cccc4c5=O)cc3)Cc2cc1OC

InChI Key InChIKey=OSFCMRGOZNQUSW-UHFFFAOYSA-N

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206310   

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universidad Nacional de Colombia

Curated by ChEMBL
LigandPNGBDBM50206310(5-Methoxy-9-oxo-9,10-dihydro-acridine-4-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 193nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia

Curated by ChEMBL
LigandPNGBDBM50206310(5-Methoxy-9-oxo-9,10-dihydro-acridine-4-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 127nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C5TPubMed