null
SMILES Clc1cccc(c1)C(c1ccc2nc[nH]c2c1)n1ccnc1
InChI Key InChIKey=UGFHIPBXIWJXNA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50176808
Affinity DataEC50: 7.00E+3nMAssay Description:The imidazole derivatives were evaluated for their retinoic acid metabolism inhibitory activity using a MCF-7 cell assay, using radiolabelled all-tra...More data for this Ligand-Target Pair
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University
Curated by ChEMBL
Cardiff University
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP26A1 in human MCF7 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair