null
SMILES FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
InChI Key InChIKey=HGVNLRPZOWWDKD-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50315213
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics
Curated by ChEMBL
Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant PI3Kalpha by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics
Curated by ChEMBL
Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant PI3Kbeta HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics
Curated by ChEMBL
Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant PI3Kgamma HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics
Curated by ChEMBL
Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant PI3Kdelta HTRF assayMore data for this Ligand-Target Pair