null

SMILES FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1

InChI Key InChIKey=HGVNLRPZOWWDKD-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50315213   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant PI3Kalpha by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MQMPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant PI3Kbeta HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MQMPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant PI3Kgamma HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MQMPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant PI3Kdelta HTRF assayMore data for this Ligand-Target Pair