null

SMILES OC(=O)c1ccc(OCCn2ccnc2)cc1

InChI Key InChIKey=XQGZSYKGWHUSDH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 7962   

TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JSZPubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JSZPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JSZPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C8289WPubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C8289WPubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C8289WPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against thromboxane A2 synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5DN7PubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5DN7PubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5DN7PubMed
TargetThromboxane-A synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Compound was tested for inhibitory activity against thromboxane synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B6VPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 1.29E+3nMAssay Description:Tested for inhibitory activity against intact human platelet TXA2 formationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9NDVPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of thromboxane synthase from human platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02S2PubMed
TargetThromboxane-A synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Compound was tested for the inhibition of thromboxane formation (thromboxane synthetase) in platelets at a concentration of 10e-4 MMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70GCDPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of human platelet thromboxane synthase (TXA2) was determined in human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2222VBHPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against human thromboxane synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CB6PubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C8289WPubMed
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JSZPubMed
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ram seminal vesicle CyclooxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5DN7PubMed
TargetThromboxane-A synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of thromboxane formation at a concentration of 10e -6 M.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24F1PRVPubMed