null

SMILES COC(=O)[C@@H]1C2CC[C@H](C[C@@H]1c1ccc(C)cc1)N2C

InChI Key InChIKey=MMKZDDDDODERSJ-GXRBRPDZSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50006781   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X4BPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KJXPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataKi:  36nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X4BPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataKi:  1.93E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KJXPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataKi:  1.93E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KJXPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X4BPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X4BPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataIC50: 23.4nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KJXPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataIC50: 3.85E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KJXPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KJXPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataIC50: 3.85E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KJXPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataIC50: 23.4nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KJXPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KJXPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X4BPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]WIN-35428l binding to Dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736RJCPubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of [3H]mazindol binding to Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736RJCPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of [3H]paroxetine binding to Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736RJCPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Binding affinity against Dopamine transporter using [3H]WIN-35 428 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BDFPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Binding affinity against serotonin transporter using [3H]paroxetine in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BDFPubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Binding affinity against Norepinephrine transporter using [3H]nisoxetine in midbrain of ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BDFPubMed