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SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12

InChI Key InChIKey=BLGXFZZNTVWLAY-SCYLSFHTSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50013515   

TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Inhibition of [3H]rauwolscine to CHO cells expressing the human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46C4PubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)copy SMILEScopy InChI
Affinity DataKi:  4.60nMAssay Description:Inhibition of [3H]rauwolscine binding to CHO cells expressing the human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46C4PubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)copy SMILEScopy InChI
Affinity DataKi:  7.5nMAssay Description:Inhibition of [3H]rauwolscine binding to CHO cells expressing the human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46C4PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)copy SMILEScopy InChI
Affinity DataKi:  45nMAssay Description:Inhibition of [3H]nitrendipine binding to membrane homogenates of rat cardiac muscle.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46C4PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)copy SMILEScopy InChI
Affinity DataKi:  289nMAssay Description:Inhibition of [3H]prazosin binding to human Alpha-1D adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46C4PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)copy SMILEScopy InChI
Affinity DataKi:  966nMAssay Description:Inhibition of [3H]prazosin binding to human Alpha-1B adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46C4PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)copy SMILEScopy InChI
Affinity DataKi:  1.06E+3nMAssay Description:Inhibition of [3H]prazosin binding to human Alpha-1A adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46C4PubMed