null

SMILES CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1

InChI Key InChIKey=BTYYWOYVBXILOJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 4566   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM4566(4-anilinoquinazoline deriv. 1 | CHEMBL91867 | N-{4...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM4566(4-anilinoquinazoline deriv. 1 | CHEMBL91867 | N-{4...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of EGF stimulated human erbB1 autophosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM4566(4-anilinoquinazoline deriv. 1 | CHEMBL91867 | N-{4...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM4566(4-anilinoquinazoline deriv. 1 | CHEMBL91867 | N-{4...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed