null

SMILES CC(C)OC(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)C(C)C)cc1

InChI Key InChIKey=RANJJVIMTOIWIN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50067485   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of [125I]leuprorelin binding to monkey recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of [125I]leuprorelin binding to rat anterior pituitary LHRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of LHRH-stimulated arachidonic acid release in CHO cells expressing human LHRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of [125I]leuprorelin binding to monkey anterior pituitary LHRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed