null
SMILES CCCOc1ccnc2[nH]cc(-c3ccnc(N)n3)c12
InChI Key InChIKey=ZHMRPXZRUZLCNL-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50371400
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of rat recombinant GST-DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in insect cellsMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2ZP46ZRPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2ZP46ZRPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in insect cellsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant GST-CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair