BindingDB

null

SMILES Oc1ccc(cc1)[C@@H]1CC(=O)c2ccc(O)cc2O1

InChI Key InChIKey=FURUXTVZLHCCNA-AWEZNQCLSA-N

PDB links: 6 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50241408

Aromatase(Homo sapiens (Human))
King's College London

Curated by ChEMBL

BDBM50241408((2S)-liquiritigenin | 7-HYDROXY-2-(4-HYDROXY-PHENY...)copy SMILEScopy InChI

IC50: 340nMAssay Description:Inhibition of human aromatase by fluorometric assayMore data for this Ligand-Target Pair

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Details Article
BindingDB Entry DOI: 10.7270/Q2CV4JN9PubMed

Targets 9 ▿
- Tyrosine-protein phosphatase non-receptor type 1 3
- Aromatase 2
- Neuraminidase 2
- Tyrosine-protein kinase Yes 1
- Xanthine dehydrogenase/oxidase 1
- Proteasome subunit beta type-5 1
- Acetylcholinesterase 1
- Estrogen receptor beta 1
- Cholinesterase 1
Publications 9 ▿
- J Nat Prod 77: 563-70 (2014) 2
- Bioorg Med Chem 16: 1474-80 (2008) 1
- Bioorg Med Chem 16: 8466-70 (2008) 1
- J Nat Prod 51: 345-348 (1988) 1
- Eur J Med Chem 167: 291-311 (2019) 1
- J Nat Prod 69: 1572-6 (2006) 1
- Bioorg Med Chem Lett 19: 5155-7 (2009) 1
- Bioorg Med Chem 19: 3378-83 (2011) 1
- Eur J Med Chem 166: 186-196 (2019) 1
Institutions 9 ▿
- [University of Innsbruck] 2
- [TBA, West China Hospital of Sichuan University, UPRES EA 4021 Biomol�cules et Th�rapies anti-tumorales, Institute, King's College London, Chosun University, Institute of Agricultural and Food Biotechnology, Korea Research Institute of Bioscience and Biotechnology] 1
- [TBA, West China Hospital of Sichuan University, UPRES EA 4021 Biomol�cules et Th�rapies anti-tumorales, Institute, King's College London, Chosun University, Institute of Agricultural and Food Biotechnology, Korea Research Institute of Bioscience and Biotechnology] 1
- [TBA, West China Hospital of Sichuan University, UPRES EA 4021 Biomol�cules et Th�rapies anti-tumorales, Institute, King's College London, Chosun University, Institute of Agricultural and Food Biotechnology, Korea Research Institute of Bioscience and Biotechnology] 1
- [TBA, West China Hospital of Sichuan University, UPRES EA 4021 Biomol�cules et Th�rapies anti-tumorales, Institute, King's College London, Chosun University, Institute of Agricultural and Food Biotechnology, Korea Research Institute of Bioscience and Biotechnology] 1
- [TBA, West China Hospital of Sichuan University, UPRES EA 4021 Biomol�cules et Th�rapies anti-tumorales, Institute, King's College London, Chosun University, Institute of Agricultural and Food Biotechnology, Korea Research Institute of Bioscience and Biotechnology] 1
- [TBA, West China Hospital of Sichuan University, UPRES EA 4021 Biomol�cules et Th�rapies anti-tumorales, Institute, King's College London, Chosun University, Institute of Agricultural and Food Biotechnology, Korea Research Institute of Bioscience and Biotechnology] 1
- [TBA, West China Hospital of Sichuan University, UPRES EA 4021 Biomol�cules et Th�rapies anti-tumorales, Institute, King's College London, Chosun University, Institute of Agricultural and Food Biotechnology, Korea Research Institute of Bioscience and Biotechnology] 1
- [TBA, West China Hospital of Sichuan University, UPRES EA 4021 Biomol�cules et Th�rapies anti-tumorales, Institute, King's College London, Chosun University, Institute of Agricultural and Food Biotechnology, Korea Research Institute of Bioscience and Biotechnology] 1
Affinity: 37 to 1.0E+5 nM▿
- IC50 12
- EC50 1
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 1