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SMILES COc1ccc2cc(ccc2c1)-c1nn(C(C)C)c2ncnc(N)c12

InChI Key InChIKey=YTSDNPLOCDVGNB-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50345739   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50345739(1-isopropyl-3-(6-methoxynaphthalen-2-yl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of human LCK using Ac-EIYGEFKKK-OH as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P2706VPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50345739(1-isopropyl-3-(6-methoxynaphthalen-2-yl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p38alpha using myelin basic protein as substrate after 180 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P2706VPubMed
TargetEphrin type-A receptor 3(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50345739(1-isopropyl-3-(6-methoxynaphthalen-2-yl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human EPHA3 using myelin basic protein as substrate after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P2706VPubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50345739(1-isopropyl-3-(6-methoxynaphthalen-2-yl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human CSK using Ac-KKKKEEIYFFF-OH as substrate after 180 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P2706VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50345739(1-isopropyl-3-(6-methoxynaphthalen-2-yl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of human EGFR using poly glu-Tyr as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P2706VPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50345739(1-isopropyl-3-(6-methoxynaphthalen-2-yl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Inhibition of human ABL using EAIYAAPFAKKK-OH as substrate by phosphorimaging methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P2706VPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50345739(1-isopropyl-3-(6-methoxynaphthalen-2-yl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 670nMAssay Description:Inhibition of human SRC using Ac-EIYGEFKKK-OH as substrate after 60 mins by phosphorimaging methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P2706VPubMed