null
SMILES CCCCC(Sc1nc(OCCc2ccccc2)cc(OCCc2ccccc2)n1)C(O)=O
InChI Key InChIKey=KYRBYBXVVWQIJQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50273683
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
ZAFES/LiFF/Goethe-University Frankfurt
Curated by ChEMBL
ZAFES/LiFF/Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of 5-lipoxygenase-mediated 5(S)-H(p)ETE formation in fMLP-stimulated human PMNL incubated 10 mins prior to fMLP challengeMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
ZAFES/LiFF/Goethe-University Frankfurt
Curated by ChEMBL
ZAFES/LiFF/Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human recombinant 5-lipoxygenase-mediated product formation from arachidonic acid after 5 to 10 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
ZAFES/LiFF/Goethe-University Frankfurt
Curated by ChEMBL
ZAFES/LiFF/Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 after 15 mins by RP-HPLC an...More data for this Ligand-Target Pair