null

SMILES CCS(=O)(=O)Nc1ccc2NC(=O)C(C(=Nc3ccc(CN4CCCCC4)cc3)c3ccccc3)c2c1

InChI Key InChIKey=SGZZQKMOFHIDKW-UHFFFAOYSA-N

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273571   

TargetAurora kinase A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273571(CHEMBL514409 | Hesperadin | N-(2-oxo-3-(phenyl(4-(...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human Aurora kinase A/TPX2 complex using gamma-[32P]ATP incubated for 1 hr by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1M0SPubMed
TargetAurora kinase B-A(Xenopus laevis)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273571(CHEMBL514409 | Hesperadin | N-(2-oxo-3-(phenyl(4-(...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Xenopus laevis Aurora kinase B/INCEP complex using gamma-[32P]ATP incubated for 1 hr by autoradiographyMore data for this Ligand-Target Pair
TargetAurora kinase B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273571(CHEMBL514409 | Hesperadin | N-(2-oxo-3-(phenyl(4-(...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human Aurora kinase B/INCEP complex expressed in Escherichia coli BL21 (DE3) using gamma-[32P]ATP incubated for 1 hr by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1M0SPubMed