null

SMILES c1cnc2c(c1)ccc1cccnc21

InChI Key InChIKey=DGEZNRSVGBDHLK-UHFFFAOYSA-N

PDB links: 10 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50092158   

TargetC-C chemokine receptor type 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataIC50: 7.40E+4nMAssay Description:Displacement of [125I]-CCL3 from human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81F7SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataEC50:  5.01E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81F7SPubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataEC50:  6.31E+3nMAssay Description:Allosteric modulation at human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as {3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81F7SPubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataEC50:  3.90E+3nMAssay Description:Allosteric modulation at human CCR8 transfected in COS7 cells assessed as [3H]IP3 turnover by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81F7SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+4nMAssay Description:Displacement of [125I]-CCL3 from human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81F7SPubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataEC50:  5.90E+3nMAssay Description:Allosteric modulation at human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as {3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81F7SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataIC50: 5.01E+4nMAssay Description:Displacement of [125I]-CCL3 from human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81F7SPubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataIC50: 7.94E+4nMAssay Description:Displacement of [125I]-CCL3 from human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81F7SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataEC50:  4.90E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81F7SPubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataEC50:  3.98E+3nMAssay Description:Allosteric modulation at human CCR8 transfected in COS7 cells assessed as [3H]IP3 turnover by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81F7SPubMed