null

SMILES Cl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21

InChI Key InChIKey=YNPFMWCWRVTGKJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 31005   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 3.89E+3nMAssay Description:Binding affinity for human cloned Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F4CPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 7.08E+3nMAssay Description:Binding affinity for human cloned Dopamine receptor D2LMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F4CPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 3.31E+3nMAssay Description:Binding affinity for human cloned Dopamine receptor D4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F4CPubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 407nMAssay Description:Binding affinity for human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F4CPubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F4CPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F4CPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells using [125I]R91150 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F4CPubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Binding affinity for human cloned Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F4CPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F4CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 3.55E+3nMAssay Description:Binding affinity for rat Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F4CPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Binding affinity for human cloned Histamine H1 receptor expressed in CHO cells using [3H]pyrilamine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F4CPubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Binding affinity for human cloned Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F4CPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 398nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F4CPubMed