null

SMILES Cc1ccc2c(cccc2n1)N1CCN(CCc2ccc3OCC(=O)Nc3c2)CC1

InChI Key InChIKey=KGVROJQOCQABGA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50412441   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50412441(CHEMBL490417 | SB-744185)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]5HT from human cloned 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0PKZPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50412441(CHEMBL490417 | SB-744185)copy SMILEScopy InChI
Affinity DataKi:  0.251nMAssay Description:Displacement of [3H]5HT from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0PKZPubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50412441(CHEMBL490417 | SB-744185)copy SMILEScopy InChI
Affinity DataKi:  0.501nMAssay Description:Displacement of [3H]5HT from human cloned 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0PKZPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50412441(CHEMBL490417 | SB-744185)copy SMILEScopy InChI
Affinity DataKi:  3.98nMAssay Description:Inhibition of [3H]5HT reuptake at SERT in rat cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0PKZPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50412441(CHEMBL490417 | SB-744185)copy SMILEScopy InChI
Affinity DataKi:  316nMAssay Description:Binding affinity at dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0PKZPubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50412441(CHEMBL490417 | SB-744185)copy SMILEScopy InChI
Affinity DataKi:  316nMAssay Description:Binding affinity at 5HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0PKZPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50412441(CHEMBL490417 | SB-744185)copy SMILEScopy InChI
Affinity DataKi:  1.26E+3nMAssay Description:Binding affinity at 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0PKZPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50412441(CHEMBL490417 | SB-744185)copy SMILEScopy InChI
Affinity DataKi:  3.98E+3nMAssay Description:Binding affinity at 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0PKZPubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50412441(CHEMBL490417 | SB-744185)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0PKZPubMed