null

SMILES COC(=O)c1ccc(cc1NC(=O)c1ccc2ccccc2n1)C(=O)Nc1ccc(CCN2CCc3cc(OC)c(OC)cc3C2)cc1

InChI Key InChIKey=FCDNRJDHYPWDHC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50293015   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293015(CHEMBL502503 | Methyl 4-((4-(2-(6,7-Dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 microplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72JRQPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293015(CHEMBL502503 | Methyl 4-((4-(2-(6,7-Dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of ABCB1 in human KBV1 cells after 10 mins by flow cytometric calcein-AM assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72JRQPubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293015(CHEMBL502503 | Methyl 4-((4-(2-(6,7-Dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ABCC2 overexpressed in MDCK cells at 100 uM by flow cytometric-based chloromethylfluorescein-diacetate accumulation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293015(CHEMBL502503 | Methyl 4-((4-(2-(6,7-Dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293015(CHEMBL502503 | Methyl 4-((4-(2-(6,7-Dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed