null
SMILES N#Cc1ccc(cc1)C1CCCc2cncn12
InChI Key InChIKey=CLPFFLWZZBQMAO-UHFFFAOYSA-N
PDB links: 2 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 8611
Affinity DataIC50: 41nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]androstenedione as substrate by 3H2O-methodMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Bologna
Curated by ChEMBL
University of Bologna
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-expressing rat NADPH-P450-reductase using progesterone as substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University of Bologna
Curated by ChEMBL
University of Bologna
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University of Bologna
Curated by ChEMBL
University of Bologna
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair