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SMILES CNc1cc(nc(N)n1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=URWCXPXBBITYLR-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152125   

TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50152125(CHEMBL3781316)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human MTH1 assessed as hydrolysis of dGTP to dGMP and pyrophosphate after 15 mins by malachite green-based microplate reade...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50152125(CHEMBL3781316)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair