null
SMILES CNc1cc(nc(N)n1)-c1cccc(Cl)c1Cl
InChI Key InChIKey=URWCXPXBBITYLR-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50152125
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
MD Anderson Cancer Center
Curated by ChEMBL
MD Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human MTH1 assessed as hydrolysis of dGTP to dGMP and pyrophosphate after 15 mins by malachite green-based microplate reade...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
MD Anderson Cancer Center
Curated by ChEMBL
MD Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair