null
SMILES CC(O)CN1CCN(CCSC(c2ccc(F)cc2)c2ccc(F)cc2)CC1
InChI Key InChIKey=MQDDJWTVOBHYHX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50199790
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
National Institute on Drug Abuse
Curated by ChEMBL
National Institute on Drug Abuse
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in whole-guinea pig brain minus cerebellum homogenates incubated for 120 mins by radioligand...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse
Curated by ChEMBL
National Institute on Drug Abuse
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]WIN35,428 from DAT in Sprague-Dawley rat brain membranes incubated for 120 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute on Drug Abuse
Curated by ChEMBL
National Institute on Drug Abuse
Curated by ChEMBL
Affinity DataKi: 101nMAssay Description:Displacement of [3H]WIN35,428 from wild type human DAT expressed in COS7 cell membranes incubated for >90 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute on Drug Abuse
Curated by ChEMBL
National Institute on Drug Abuse
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibition of DAT (unknown origin) expressed in COS7 cells assessed as reduction in [3H]DA uptake incubated for 5 mins by beta-scintillation counting...More data for this Ligand-Target Pair
Affinity DataKi: 424nMAssay Description:Displacement of [3H]N-methylspiperone from human D3R expressed in HEK293 cell membranes incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 693nMAssay Description:Displacement of [3H]N-methylspiperone from human D2R expressed in HEK293 cell membranes incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse
Curated by ChEMBL
National Institute on Drug Abuse
Curated by ChEMBL
Affinity DataKi: 1.77E+3nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brain stem membranes incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.30E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D4R expressed in HEK293 cell membranes incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at DRD2 (unknown origin) expressed in HEK293T cells transfected with Galphai1-RLuc8 and gamma2-GFP10 assessed as inhibition of qu...More data for this Ligand-Target Pair