null

SMILES Clc1ccc(Cn2c3sc4CN(CC5CC5)CCc4c3c3ncnn3c2=O)cc1

InChI Key InChIKey=KGQCLTUHOICIST-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 289615   

LigandPNGBDBM289615(6-(4-Chlorobenzyl)-9-(cyclopropylmethyl)-8,9,10,11...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of full length GST-tagged PDE1B (unknown origin) assessed as decrease in FAM-cAMP hydrolysis preincubated for 5 mins followed by FAM-cAMP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DP3PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Dart Neuroscience LLC

Curated by ChEMBL
LigandPNGBDBM289615(6-(4-Chlorobenzyl)-9-(cyclopropylmethyl)-8,9,10,11...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE10A1 (unknown origin) assessed as decrease in FAM-cAMP hydrolysis after 1 hr by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DP3PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Dart Neuroscience LLC

Curated by ChEMBL
LigandPNGBDBM289615(6-(4-Chlorobenzyl)-9-(cyclopropylmethyl)-8,9,10,11...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DP3PubMed