null
SMILES ONC(=O)CCCCCN1C(=O)c2cccc3cccc(C1=O)c23
InChI Key InChIKey=JTDYUFSDZATMKU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50328678
TargetHistone deacetylase 1(Homo sapiens (Human))
Washington University School of Medicine
Curated by ChEMBL
Washington University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of full length human C-terminal FLAG/His-tagged KDAC1 expressed in baculovirus expression system using substrate A after 60 mins by microf...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Washington University School of Medicine
Curated by ChEMBL
Washington University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of full length human C-terminal His-tagged KDAC3/N-terminal GST-tagged human NCOR2 (395 to 489 residues) expressed in baculovirus expressi...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Washington University School of Medicine
Curated by ChEMBL
Washington University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human KDAC6 expressed in baculovirus expression system using FITC-Histone 4 acetylated peptide as substrate after 60 mins by microfluid...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University School of Medicine
Curated by ChEMBL
Washington University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University School of Medicine
Curated by ChEMBL
Washington University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 6.81E+3nMAssay Description:Inhibition of full length human C-terminal His-tagged KDAC8 expressed in baculovirus expression system using (FAM)-labeled peptide as substrate after...More data for this Ligand-Target Pair