null
SMILES C[C@@H](Nc1nc(NC2Cc3ccccc3C2)nc(n1)-c1cccc(n1)C(F)(F)F)C1CC1
InChI Key InChIKey=QNCFEEZALZKPFF-CYBMUJFWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 279913
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Agios Pharmaceuticals, Inc.
US Patent
Agios Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 50nMpH: 6.5 T: 2°CAssay Description:In the primary reaction, the reduction of α-KG acid to 2-HG is accompanied by a concomitant oxidation of NADPH to NADP. The amount of NADPH rema...More data for this Ligand-Target Pair