null
SMILES C[C@H](O)C(=O)N1CCC(CC1)n1c2c(cnc3ccc(nc23)-c2cccc3[nH]ncc23)n(C)c1=O
InChI Key InChIKey=YVXILUOSLZRLOG-AWEZNQCLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50428108
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Pfizer Inc.
US Patent
Pfizer Inc.
US Patent
Affinity DataKi: 0.721nM ΔG°: -12.5kcal/molepH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kalpha using an in vitro kinase assay. PI3-Kalpha activity is measured in v...More data for this Ligand-Target Pair
Affinity DataKi: 2.63nM ΔG°: -11.7kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair