null
SMILES CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2CN(C2)C(c2ccccc2)c2ccccc2)cc1F
InChI Key InChIKey=KSBYUWHBUZLDDL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 145635
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.; Genentech, Inc.
US Patent
Xenon Pharmaceuticals Inc.; Genentech, Inc.
US Patent
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) was tritiated. Three tritiums were incorporated in plac...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.; Genentech, Inc.
US Patent
Xenon Pharmaceuticals Inc.; Genentech, Inc.
US Patent
Affinity DataIC50: 2.54E+3nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.; Genentech, Inc.
US Patent
Xenon Pharmaceuticals Inc.; Genentech, Inc.
US Patent
Affinity DataIC50: 14nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair