null

SMILES OC(=O)Cc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=QRZAKQDHEVVFRX-UHFFFAOYSA-N

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 223312   

TargetCaspase-1(Homo sapiens (Human))
University of Colorado

LigandPNGBDBM223312(Felbinac)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53JQXPubMed
TargetCaspase-3(Homo sapiens (Human))
University of Colorado

LigandPNGBDBM223312(Felbinac)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53JQXPubMed
TargetCaspase-4(Homo sapiens (Human))
University of Colorado

LigandPNGBDBM223312(Felbinac)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53JQXPubMed
TargetCaspase-5(Homo sapiens (Human))
University of Colorado

LigandPNGBDBM223312(Felbinac)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53JQXPubMed
TargetCaspase-9(Homo sapiens (Human))
University of Colorado

LigandPNGBDBM223312(Felbinac)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53JQXPubMed