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SMILES Nc1c(Cl)cc(cc1Cl)S(N)(=O)=O

InChI Key InChIKey=DVZMRTJKNJKEGV-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11608   

TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Università degli Studi di Firenze

LigandPNGBDBM11608(β-CA inhibitor, 7 | 4-Amino-3,5-dichlorobenze...)copy SMILEScopy InChI
Affinity DataKi:  1.26E+3nM ΔG°:  -8.04kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9V4FPubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Università degli Studi di Firenze

LigandPNGBDBM11608(β-CA inhibitor, 7 | 4-Amino-3,5-dichlorobenze...)copy SMILEScopy InChI
Affinity DataKi:  2.66E+3nM ΔG°:  -7.60kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9V4FPubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis)
Università degli Studi di Firenze

LigandPNGBDBM11608(β-CA inhibitor, 7 | 4-Amino-3,5-dichlorobenze...)copy SMILEScopy InChI
Affinity DataKi:  4.14E+3nM ΔG°:  -7.34kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9V4FPubMed