null
SMILES Cc1n[nH]c(C)c1-c1cc(cc2nc([nH]c12)C1CC1(F)F)-c1c(C)noc1C
InChI Key InChIKey=RMCZCJRPBQPLJA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 249288
Affinity DataIC50: 161nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Gilead Sciences, Inc.
US Patent
Gilead Sciences, Inc.
US Patent
Affinity DataIC50: 94.1nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 25.1nMpH: 7.5 T: 2°CAssay Description:Binding of the bromodomain BRD4-I to an acetylated histone H4 peptide was measured using a bead-based Amplified Luminescent Proximity Homogeneous Ass...More data for this Ligand-Target Pair