null
SMILES CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)c(NC(=O)C=C)c1
InChI Key InChIKey=MBWRLLRCTIYXDW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 249396
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Compounds were profiled for FGFR inhibition activity at Reaction Biology Corporation (Malvern, Pa.) with their Kinase HotSpot assay. See, Anastassiad...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 1.98E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were profiled for FGFR inhibition activity at Reaction Biology Corporation (Malvern, Pa.) with their Kinase HotSpot assay. See, Anastassiad...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were profiled for FGFR inhibition activity at Reaction Biology Corporation (Malvern, Pa.) with their Kinase HotSpot assay. See, Anastassiad...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 173nMpH: 7.5 T: 2°CAssay Description:Compounds were profiled for FGFR inhibition activity at Reaction Biology Corporation (Malvern, Pa.) with their Kinase HotSpot assay. See, Anastassiad...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Compounds were profiled for FGFR inhibition activity at Reaction Biology Corporation (Malvern, Pa.) with their Kinase HotSpot assay. See, Anastassiad...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Recombinant FGFR1 (2.5 nM), or FGFR4 (12 nM) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ ID NO:1) (20 μM, FGFR1 substrate); Pol...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 513nMpH: 7.5 T: 2°CAssay Description:Recombinant FGFR1 (2.5 nM), or FGFR4 (12 nM) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ ID NO:1) (20 μM, FGFR1 substrate); Pol...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 173nMpH: 7.5 T: 2°CAssay Description:Compounds were profiled for FGFR inhibition activity at Reaction Biology Corporation (Malvern, Pa.) with their Kinase HotSpot assay. See, Anastassiad...More data for this Ligand-Target Pair