null

SMILES CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)c(NC(=O)C=C)c1

InChI Key InChIKey=MBWRLLRCTIYXDW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 249396   

TargetFibroblast growth factor 4(Homo sapiens (Human))
Eisai R&D Management Co., LTD.

US Patent
LigandPNGBDBM249396(US10537571, Compound 108 | US10562888, Compound 10...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Recombinant FGFR1 (2.5 nM), FGFR2 (1 nM), FGFR3 (5 nM), or FGFR4 (12 nM) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ ID NO:1) (20 &#...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3PKSUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Eisai R&D Management Co., LTD.

US Patent
LigandPNGBDBM249396(US10537571, Compound 108 | US10562888, Compound 10...)copy SMILEScopy InChI
Affinity DataIC50: 173nMAssay Description:Recombinant FGFR1 (2.5 nM), FGFR2 (1 nM), FGFR3 (5 nM), or FGFR4 (12 nM) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ ID NO:1) (20 &#...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3PKSUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., LTD.

US Patent
LigandPNGBDBM249396(US10537571, Compound 108 | US10562888, Compound 10...)copy SMILEScopy InChI
Affinity DataIC50: 1.98E+3nMAssay Description:Recombinant FGFR1 (2.5 nM), FGFR2 (1 nM), FGFR3 (5 nM), or FGFR4 (12 nM) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ ID NO:1) (20 &#...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3PKSUS Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Eisai R&D Management Co., LTD.

US Patent
LigandPNGBDBM249396(US10537571, Compound 108 | US10562888, Compound 10...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Recombinant FGFR1 (2.5 nM), FGFR2 (1 nM), FGFR3 (5 nM), or FGFR4 (12 nM) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ ID NO:1) (20 &#...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3PKSUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Eisai R&D Management Co., LTD.

US Patent
LigandPNGBDBM249396(US10537571, Compound 108 | US10562888, Compound 10...)copy SMILEScopy InChI
Affinity DataIC50: 173nMAssay Description:Recombinant FGFR1 (2.5 nM), FGFR2 (1 nM), FGFR3 (5 nM), or FGFR4 (12 nM) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ ID NO:1) (20 &#...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3PKSUS Patent
TargetFibroblast growth factor 4(Homo sapiens (Human))
Eisai R&D Management Co., LTD.

US Patent
LigandPNGBDBM249396(US10537571, Compound 108 | US10562888, Compound 10...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Recombinant FGFR1 (2.5 nM), FGFR2 (1 nM), FGFR3 (5 nM), or FGFR4 (12 nM) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ ID NO:1) (20 &#...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3PKSUS Patent