null
SMILES CN(C(=O)CN1CCN(C)CC1)c1ccc(N\C(=C2/C(=O)Nc3ccc(cc23)C(O)=O)c2ccccc2)cc1
InChI Key InChIKey=NOMBUNHXDWBICV-DQSJHHFOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50248938
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
US Patent
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
US Patent
Affinity DataKi: 0.680nMAssay Description:MELK and its substrate, Bcl-G were both recombinantly expressed and purified for use in screening assays (See Methods). 752 compounds from an in-hous...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
US Patent
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
US Patent
Affinity DataKi: 4.90nMAssay Description:Candidates for inhibitor selectivity characterization were chosen based on an initial single-timepoint commercial kinome profiling screen performed w...More data for this Ligand-Target Pair
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
US Patent
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
US Patent
Affinity DataKi: 8.60nMAssay Description:Candidates for inhibitor selectivity characterization were chosen based on an initial single-timepoint commercial kinome profiling screen performed w...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
US Patent
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
US Patent
Affinity DataKi: 81nMAssay Description:Candidates for inhibitor selectivity characterization were chosen based on an initial single-timepoint commercial kinome profiling screen performed w...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
US Patent
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
US Patent
Affinity DataKi: 85nMAssay Description:Candidates for inhibitor selectivity characterization were chosen based on an initial single-timepoint commercial kinome profiling screen performed w...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
US Patent
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
US Patent
Affinity DataKi: 1.90E+4nMAssay Description:Candidates for inhibitor selectivity characterization were chosen based on an initial single-timepoint commercial kinome profiling screen performed w...More data for this Ligand-Target Pair
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
US Patent
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
US Patent
Affinity DataIC50: 5.20nMAssay Description:The top 10 hits from the 1 μM screening and derivatives of MELK-In-1 were subjected to the same assay conditions with varied inhibitor concentra...More data for this Ligand-Target Pair