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SMILES CN1CCc2ccc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)cc2C1=O

InChI Key InChIKey=RDGPIFCCGRDXMY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 423299   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
NHWA PHARMA. CORPORATION

US Patent
LigandPNGBDBM423299(US10501452, Compound 5)copy SMILEScopy InChI
Affinity DataKi:  2.40nMAssay Description:5-HT1A: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1FR6US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
NHWA PHARMA. CORPORATION

US Patent
LigandPNGBDBM423299(US10501452, Compound 5)copy SMILEScopy InChI
Affinity DataKi:  9.10nMAssay Description:Displacement of [3H](+)8-OH-DPAT from rat cerebral cortex 5HT1A receptor measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8K6MPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA
LigandPNGBDBM423299(US10501452, Compound 5)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Antagonist activity at human 5HT1A receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium flux incubated for 60 mins at 37 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8K6MPubMed