null
SMILES Fc1ccc(cc1Cl)C(=O)N1CCC(F)(CNCCNc2ccccc2)CC1
InChI Key InChIKey=BZPOPHHMWUCUHD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 433532
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataKi: 1.30nMAssay Description:5-HT1A: Radioligand binding was performed using membranes from CHO-K1 cells stably transfected with the human 5-HT1A receptor. All assays were carrie...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataEC50: 105nMAssay Description:Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as increase in calcium mobilization measured a...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataEC50: 26nMAssay Description:Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as increase in ERK1/2 phosphorylation levels i...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataEC50: 186nMAssay Description:Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumu...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataEC50: 2.00E+3nMAssay Description:Biased agonist activity at Gal4-VP16 transcription factor linked human 5-HT1A receptor expressed in human U2OS cells assessed as stimulation of beta-...More data for this Ligand-Target Pair