null

SMILES COc1cc(C[C@@H](C)N)c(OC)cc1I

InChI Key InChIKey=BGMZUEKZENQUJY-SSDOTTSWSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50133231   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))TBA
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT2B receptor expressed in CHO cells by radioligand completion assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9VBRPubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))TBA
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5ZQWPubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))TBA
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibitory constant against cloned human 5-hydroxytryptamine 2B receptor using with [125I]- DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z320C1PubMed
Target5-hydroxytryptamine receptor 2B(RAT)
Alcon Research, Ltd

Curated by ChEMBL
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataEC50:  11.9nMAssay Description:Agonist activity at 5HT2B receptor in rat stomach fundus assessed as intracellular calcium mobilization relative to 5HTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R7BPubMed
Target5-hydroxytryptamine receptor 2B(RAT)
Alcon Research, Ltd

Curated by ChEMBL
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Activity against 5HT2B receptor in longitudinal stomach fundus strips in wistar ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5ZQWPubMed