null

SMILES [H][C@@]12C[C@@]([H])(C=C1)[C@@H]([C@@H]2Nc1nc(Nc2ccc3C[C@H](CCCc3c2OC)N2CCN(C)CC2)ncc1Cl)C(N)=O

InChI Key InChIKey=FLTLUXCGVBUQLQ-PDULFCFVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193808   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Teva Branded Pharmaceutical Products R&D

Curated by ChEMBL
LigandPNGBDBM50193808(CHEMBL3936443)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human ALK expressed in baculovirus using recombinant GST PLC-gamma as substrate assessed as phosphorylation of the substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DC2PubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Teva Branded Pharmaceutical Products R&D

Curated by ChEMBL
LigandPNGBDBM50193808(CHEMBL3936443)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of NPM-ALK phosphorylation in human SUP-M2 cells after 2 to 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DC2PubMed