null

SMILES COc1cc(ccc1Nc1ncc2NC(=O)c3ccccc3N(C)c2n1)N1CCN(C)CC1

InChI Key InChIKey=LGLHCXISMKHLIK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50337126   

TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50337126(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)copy SMILEScopy InChI
Affinity DataKd:  15nMAssay Description:In vitro biochemical assays were performed in parallel to determine the most potent tool compound.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7T57PubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50337126(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)copy SMILEScopy InChI
Affinity DataKd:  2nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H996XCPubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50337126(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)copy SMILEScopy InChI
Affinity DataKd:  15nMMore data for this Ligand-Target Pair
In DepthDetails
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50337126(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of tracer 236 binding to recombinant human GST-tagged TNK2 catalytic domain (110 to 476 residues) expressed in baculovirus expression syst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q7SPubMed