null

SMILES NC(=O)c1c(NC(=O)NCCCCN2CCCC2)snc1OCc1c(F)cc(Br)cc1F

InChI Key InChIKey=HXHAJRMTJXHJJZ-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25115   

TargetAngiopoietin-1 receptor(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 10.1nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant TIE2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M07PVPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Inhibition of human recombinant Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KD2PubMed